Pharmaceutical Raw Material USP Grade Clobetasol Propionate Powder

• Customization: Available
• Powder: Yes
• Customized: Customized
• Certification: GMP
• Suitable for: Adult
• Purity: >99%
• Stock: in Stock
• Payment: Paypal/Western Union/Bank Transfer/Bitcoin
• Production-Capacity: 50000 Kilograms Per Month
• Transport Package: Alumininum Foil Bags
• Specification: 1kg or customized
• Trademark: QDAnia
• Origin: China

Product Description

 

Product Description

Pharmaceutical Raw Material USP Grade Clobetasol Propionate Powder
 

Name: Clobetasol propionate
C.A.S NO. : 25122-46-7
Synonyms: 21-Chloro-9-fluoro-11b,17-dihydroxy-16b-methylpregna-1,4-diene-3,20-dione 17-propionate
EINECS NO.: 246-634-3
Molecular formula: C25H32ClFO5
Molecular weight : 466.97
Assay: 99%
Characteristic: White crystalline powder

Clobetasol propionate is a corticosteroid of the glucocorticoid class used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis caused by exposure to poison ivy/oak. Clobetasol belongs to US Class I of the corticosteroids,

making it one of the most potent available. It comes in shampoo, mousse, ointment and emollient cream presentations. It has very high potency and typically should not be used with occlusive dressings, or for extended continuous use (beyond two weeks). It is also used to treat several autoimmune diseases including alopecia areata, lichen sclerosus, and lichen planus.

 

 

 

 

Function and Application

Function
 

1. Anti-inflammatory effects: The product can reduce and prevent tissue response to inflammation, thereby reducing inflammation performance. Hormone suppression of inflammatory cells, including leukocytes and macrophages accumulation in sites of inflammation and inhibition of phagocytosis, lysosomal enzyme release and synthesis and release of inflammatory chemical mediators. Can reduce and prevent tissue response to inflammation, thereby reducing inflammation performance.

2. Immunosuppressive effect: preventing or inhibiting cell-mediated immune response, delayed hypersensitivity reactions, reducing T lymphocytes, monocytes, eosinophils, reducing immunoglobulin binding to cell surface receptors and inhibition of the synthesis and release of interleukin, thus reducing the T lymphocyte transformation of lymphoblastoid cells, and reduce the extension of the primary immune response. Can reduce immune complexes through the basement membrane, and can reduce the concentration of ingredients complement and immunoglobulins.

 

 

Certifications

Item	Specification	Results
Appearance	white to cream,crystalline powder	White crystalline powder
Identification (by IR)	Confirms to the CRS spectrum	Confirm
Melting point	Approximately 196ºC	196ºC
Specific rotation	+98°~+104°(dried substance)	+78.0°
Loss on drying	≤ 2.0%	0.2%
Residue on ignition	≤0.1%	0.04%
Heavy metals	≤20ppm	Confirm
Related substances(by HPLC)	Any impurity≤1.0% Total impurities≤2.5%	0.15% 0.15%
Assay(by HPLC)	Contains 97.0% to 102.0% of C25H32ClFO5 Calculated on dried basis	100.4%
Residual solvents	Ethanol ≤ 3000ppm Aceto ne ≤ 500ppm Pyrid ine ≤ 100ppm N,N-Dimethylfor mamide ≤ 100ppm	269ppm <4ppm <3ppm <10ppm

 

Packaging & Shipping

 

MOQ KG	SHIPPING	TIME
1-10KG	BY EXPRESS	7-10 DAYS
10KG+	BY AIR	12-15 DAYS
25KG+	BY AIR/SEA	15-22 DAYS/30-35DAYS/      40-45DAYS  (Depending On The Country)

Company Profile

 

Qingdao Ania Biotechnology Co., Ltd. stands at the forefront of innovation, specializing in the research, development, and production of top-tier API raw materials, plant extracts, and peptide products. Our unwavering dedication is to deliver safe and effective chemical raw materials and bioactive ingredients to a global clientele, spanning nutrition, health, beauty, and more. Harnessing cutting-edge production technology, a rigorous quality control system, and pioneering R&D capabilities, we drive industry advancement and cater to the diverse needs of our customers. Our guiding principle of 'quality first, customer first' ensures that we consistently provide unparalleled solutions and products to our valued clients.

1. Who are we?
Located in the vibrant city of Qingdao, Shandong province, China, since 2011, we excel in the research, development, production, and technical services of organic silicone and organic fluoro chemicals. With over two decades of expertise, we have carved a niche in the development and production of silicone and fluoro chemicals.

2. How can we guarantee quality?
We ensure excellence with a pre-production sample before initiating mass production;
A thorough final inspection is conducted before shipment to ensure quality assurance;

3.What can you buy from us?
Our product range includes premium Organic silicone oils, Organic siloxanes, and more.

4. Why should you buy from us not from other suppliers?
1). Our dynamic and innovative R&D team.
2). We offer flexible quantized production capabilities, ranging from grams to tons;
3). Our facilities house a diverse array of state-of-the-art laboratory and plant equipment;
4) .We adhere to stringent QC standards tailored to satisfy customer requirements, equipped with advanced analysis and assay tools;
5). Our logistics solutions ensure efficient and safe transport of chemical products;
6) . We provide exceptional after-sale support to our customers.
7). We guarantee the highest quality products, coupled with excellent packaging
8 ). Our commitment to excellence is backed by an ISO certification

5. what services can we provide?
We accommodate various Delivery Terms: EXW, FOB, CFR, CIF, CIP, DDP
We accept Payment in diverse Currencies: USD, EURO, RMB
Flexible Payment Types accepted: T/T, Letter of Credit, PayPal, Western Union
We communicate fluently in English

FAQ

 

Q1: May I get one sample before placing order?
A: Yes, Sample are available. For normal products, samples are for free and you just need to bear the freight; For those high value products, you just need to freight and certain product cost. When we both cooperate for some times or when you are our VIP customer, free sample will be offered when you need.Mutual effort towards each other.

Q2: Can you provide relevant documents?
A:Of course. We can provide Commercial Invoice, Packing List, Bill of loading, COA, Health certificate and Origin certificate.If
your markets have any special requirements, just let us know.

Q3: Which payment is available for your company?
A: T/T, Western Union,Bank Transfer,Paypal or Bitcoins usdt trc usdt erc and so on. You can choose the way which is convenient for you.

Q4: How and when can I get my goods after payment?
A: Delivery/ lead time: goods will be sent after payment within 12- 24hours, and domestic shipped to forwarders need 1~2 working days ,then by Air from Hongkong to your country 3~5 days by express .DHL Express just 3~4days delivery,UPS/USPS 7~12days.
About the double clearance ways by air:Sometimes the international shipping need to wait the airlines flight 1~5days,Then shipped 5~7days delivery.So total It takes 7-15 days to sign for special parcels from China abroad,but it is more safe than express ways(almost 100% success delivery).

For large quantity products,shipping by sea is worthwhile(by air double clearance ways no problem).It will cost days to weeks to come to your port, It depends on where the port is.
we have 12 years experience to ship cargo ,Supporting CFR,CNF ,FOB too,Double clearance ways by air or overseas warehouses local stock.

Q5: Is there any possible to use my appointed label or package?
A: Yes. If needed, we'd like to use label or package according to your requirement.

Q6:How to ensure quality?Do you accept third party inspection?
A:Firstly ,we will confirm with you the product standard and send you the COA .We will put your sample orders to the Lab making the COA or HPLC for you immediately,100% test before sent to customers,International Authorized Third-Party Test for the products if you need are highly welcomed.

Q7: How do you treat quality complaint?If the inspection result can not meet the agreement between the two sides, can you bear all the losses caused by this?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us,we will send you free goods for replacement or refund your loss.

Q8 :Can your company accept the special requirements of your customers?
A:Of course, we can.